Cytochromes P450 and
Skin Cancer: Role of Local Endocrine Pathways
Author(s):
Andrzej T. Slominski, Michal A. Zmijewski,
Igor Semak, Blazej Zbytek, Alexander Pisarchik, Wei Li, Jordan Zjawiony and
Robert C. TuckeyPages 77-96 (20)
Abstract:
Skin is the largest body organ forming a
metabolically active barrier between external and internal environments. The
metabolic barrier is composed of cytochromes P450 (CYPs) that regulate its
homeostasis through activation or inactivation of biologically relevant
molecules. In this review we focus our...