Most Accessed Article: Fibroblast Growth Factor Receptor (FGFR): A New Target for Non-small Cell Lung Cancer Therapy
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Wednesday, December 28, 2016
Thursday, December 22, 2016
Wednesday, December 14, 2016
Podcast for (Nutrition, Nitrogen Requirements, Exercise and Chemotherapy-Induced Toxicity in Cancer Patients. A puzzle of Contrasting Truths?)
Podcast for (Nutrition, Nitrogen Requirements, Exercise and Chemotherapy-Induced Toxicity in Cancer Patients. A puzzle of Contrasting Truths?)
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Tuesday, December 13, 2016
Thursday, December 8, 2016
Wednesday, November 30, 2016
Highlighted Article: Brain-metastatic Breast Cancer: Clinical Considerations and Pharmacological Approaches
Highlighted Article: Brain-metastatic Breast Cancer: Clinical Considerations and Pharmacological Approaches
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Thursday, November 24, 2016
Monday, November 21, 2016
Tuesday, November 8, 2016
Call For Paper
Bentham Science Publishers would like to invite you to submit your research paper for publishing in the Journal of
Anti Cancer Agents in Medicinal Chemistry
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Wednesday, November 2, 2016
Highlighted Article: Molecular Mechanisms of Anti-cancer Activities of β-elemene: Targeting Hallmarks of Cancer
Molecular Mechanisms of Anti-cancer Activities of β-elemene: Targeting Hallmarks of Cancer
Author(s):
Shiyu Jiang, Chunhua Ling, Wei Li, Hongxin Jiang, Qiaoming Zhi and Min Jiang Pages 1426 - 1434 (9)
Abstract:
Increasing knowledge on the hallmark characteristics of cancer and tumor pharmacology has promoted the introduction of phytochemicals, such as traditional Chinese medicine (TCM) in cancer therapy, which modulate numerous molecular...
Tuesday, October 25, 2016
Most Cited Article: Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways
Cytochromes P450 and
Skin Cancer: Role of Local Endocrine Pathways
Author(s):
Andrzej T. Slominski, Michal A. Zmijewski,
Igor Semak, Blazej Zbytek, Alexander Pisarchik, Wei Li, Jordan Zjawiony and
Robert C. TuckeyPages 77-96 (20)
Abstract:
Skin is the largest body organ forming a
metabolically active barrier between external and internal environments. The
metabolic barrier is composed of cytochromes P450 (CYPs) that regulate its
homeostasis through activation or inactivation of biologically relevant
molecules. In this review we focus our...
Wednesday, October 19, 2016
Tuesday, October 4, 2016
New Issue ::: Anti-Cancer Agents in Medicinal Chemistry, 16 Issue 8
Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.
Each issue contains a series of timely in-depth reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.
Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist...
Thursday, June 23, 2016
Disintegrins from Snake Venoms and their Applications in Cancer Research and Therapy
Author(s):
Jessica Kele Arruda Macedo, Jay W. Fox and Mariana de Souza CastroPages 532-548 (17)
Abstract:
Integrins regulate diverse functions in cancer pathology and in tumor cell development and contribute to important processes such as cell shape, survival, proliferation, transcription, angiogenesis, migration, and invasion. A number of snake venom proteins have the ability to interact with integrins. Among these are the disintegrins, a family...
Targeting EZH2 for Cancer Therapy: Progress and Perspective
Author(s):
Chi Han Li and Yangchao ChenPages 559-570 (12)
Abstract:
Enhancer of Zeste Homolog 2 (EZH2) is the core component of the polycomb repressive complex 2 (PRC2), possessing the enzymatic activity in generating di/tri-methylated lysine 27 in histone H3. EZH2 has important roles during early development, and its dysregulation is heavily linked to oncogenesis in various tissue types. Accumulating evidences suggest a remarkable therapeutic...
Mutations of Chromatin Structure Regulating Genes in Human Malignancies
Author(s):
Jian Chen, Franklin H. Herlong, John R. Stroehlein and Lopa MishraPages 411-437 (27)
Abstract:
Chromatin structure regulating processes mediated by the adenosine triphosphate (ATP) – dependent chromatin remodeling complex and the covalent histone-modifying complexes are critical to gene transcriptional control and normal cellular processes, including cell stemness, differentiation, and proliferation. Gene mutations, structural abnormalities,...
The Melanocortin Receptor System: A Target for Multiple Degenerative Diseases
Author(s):
Minying Cai and Victor J. HrubyPages 488-496 (9)
Abstract:
The melanocortin receptor system consists of five closely related G-protein coupled receptors (MC1R, MC2R, MC3R, MC4R and MC5R). These receptors are involved in many of the key biological functions for multicellular animals, including human beings. The natural agonist ligands for these receptors are derived by processing of a primordial animal gene product, proopiomelanocortin...
